Medicine (Oncology): Funded PhD Studentship at Swansea University: Therapeutic exosomes as novel treatment for ovarian cancer
- Full cost of UK/EU tuition fees, plus a stipend
- Deadline: August 23, 2017
Swansea University is a UK top 30 institution for research excellence (Research Excellence Framework 2014), and has been named Welsh University of the Year 2017 by The Times and Sunday Times Good University Guide.
Swansea University Medical School, in association with Health and Care Research Wales (HCRW), invites applications for a fully-funded 3 year PhD studentship.
Subject areas: Oncology and drug development
Start date: 1 October 2017
Ovarian cancer is the fifth most common cause of cancer death in women and accounts for more UK deaths than all of the other gynaecological cancers put together. Over 7,000 women are diagnosed with ovarian cancer every year in the UK and 4,200 will die. Symptoms of ovarian cancer are often vague early on and many women are not diagnosed until after the cancer has grown and spread to other parts of the body. Less than half of women with ovarian cancer survive five years from diagnosis with many not responding to current treatments. Platinum-based drugs (such as cisplatin and carboplatin) are the most widely used chemotherapy drugs in ovarian carcinoma (85% patients will receive this treatment), but their efficacy is not satisfactory.
This proposal aims to investigate whether exosomes may influence the growth of ovarian cancer cells in vitro. In addition, these novel drugs will also be assessed in combination with current treatments including cisplatin to determine their potential benefit for combination therapy.
The student will be supervised by the Reproductive Biology and Gynaecological Oncology Group academics, Dr Deya Gonzalez and Prof Steve Conlan, joining a vibrant, multidisciplinary research environment composed of academics, clinicians, PhD students, post-docs and technicians.
Applicants should have a first class or 2.1 degree in molecular biology, medical genetics, genetics, biochemistry or a related discipline.
Applications are sought from individuals with experience in:
- Gene/Protein expression analysis (Quantitative Real Time PCR, Western blot, ELISA)
- Tissue culture techniques
- Flow cytometry
Applicants with previous experience working with patient samples are encouraged to apply.
Applicants whose first language is not English are expected to pass IELTS (International English Language Testing System) at grade 6.5.
Due to funding restrictions, this studentship is open to UK/EU candidates only.
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The studentship covers the full cost of UK/EU tuition fees, plus an annual stipend of £14,200 for up to 3 years.
Funds to cover research costs and attendance to scientific conferences are available for the duration of the project.
Please visit our website for more information.
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