Medical and HealthCare Studies: Tuition Fee ONLY MSc by Research Scholarship at Swansea
- UK/EU tuition fee only
- 1 May 2020
Medical and Health Care Studies: Tuition Fee ONLY RMS Foundation MSc by Research Scholarship: Staphylococcus epidermidis and host immune factors in medical device infections
This scholarship is funded by the RMS Foundation, Switzerland.
Subject areas: Microbiology, Immunology, Material science
**Healthcare acquired infections associated with medical devices such as intravenous catheters, joint prostheses, shunts and heart valves are caused by Staphylococcus epidermidis, a common constituent of the skin and mucus membranes of humans. This project aims to investigate the relationship between S. epidermidis, host immune factors and biomaterial surfaces. A collection of clinical S. epidermidis strains, relevant biomaterial surfaces, an ex vivo whole blood model, cell culture, confocal microscopy (CLSM), scanning electron microscopy (SEM), quantitative PCR (qPCR), and ELISAs will be used. The work will be divided into two parts: Part 1 will determine S. epidermidis and host and cellular responses at transcriptional and protein levels in the presence of titanium (Ti) and titanium alloy (Ti6Al4V) surfaces; and Part 2 will examine the influence of pre-coating Ti and Ti6Al4V surfaces with host-derived proteins on S. epidermidis colonisation and accumulation. Samples in part 1 and 2 will also be imaged using CLSM and SEM to visualise changes.
Supervisor: Dr. Llinos Harris (Senior Lecturer Microbiology and Infectious Disease)
Group: Microbiology and Infectious Diseases, Swansea University Medical School
Facilities: The research facilities include modern laboratories equipped with the latest instrumentation for biomolecular analysis such as Zeiss CLSM, Hitachi SEM, Agilent Seahorse analyser, flow cytometry, DNA sequencing, and mass spectrometry. These facilities enable delivery of research by the Microbiology and Infectious Disease group, which specialises in medical devices-related infections such as staphylococcal biofilms.
Postgraduate Research students are considered inclusive members of the School’s research team. They have access to a diverse programme of seminars and workshops and a comprehensive skills’ development programme. Throughout their candidature, the student will be supported by a supervisory team, in this case, Dr Llinos G Harris and Dr Thomas Wilkinson (Associate Professor Microbiology and Infectious Disease); as well as a dedicated PGR Office team and Higher Degrees Committee.
Candidates should have a minimum of 2.1 honours degree (or its equivalent) in Microbiology, Immunology, Genetics, Medical Engineering, Biology or a relevant discipline. Experience in microbiology is very desirable. Cell or blood work experience is desirable.
We would normally expect the academic and English Language requirements to be met by point of application. For details on the University’s English Language entry requirements, please visit our website.
Due to funding restrictions, this scholarship is open to UK/EU candidates only.
This scholarship covers the full cost of UK/EU tuition fees ONLY.
Please visit our website for more information.
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