Life Sciences: Celtic Advanced Life-science Innovation Network (CALIN) Funded PhD Studentship: Applications for Three Dimensional (3D) Cell Culture Models

  • Phd
  • The studentship covers the full cost of UK/EU tuition fees, plus a tax free stipend of ÂŁ14,553 p.a.
  • 21 July 2017

A PhD studentship is available, funded by the Ireland Wales 2014-2020 European Territorial Co-operation (ETC) programme on the project entitled Celtic Advanced Life-science Innovation Network (CALIN).
Applications for three dimensional (3D) cell culture models are becoming increasingly prevalent in contemporary cancer research and drug resistance studies. Cell culture in 3D provides a more physiologically relevant microenvironment. Collagen based scaffolds that can mimic the natural extra cellular matrix (ECM) found in vivo, can be engineered to be biocompatible, biodegradable and non-toxic with a pore structure that facilitates the infiltration of cells and nutrients. The development and use of such scaffolds for the in vitro culture of various ovarian cancer cells, in a 3D environment, is now recognised to offer potential to enhance our understanding of disease mechanisms and pathology with a resulting improvement in treatment outcomes. Integrating industrial scale engineering and manufacturing with academic knowledge surrounding advanced cell culture systems and cell based therapies, this project aims to develop advanced oncology therapeutic strategies in vitro. Throughout the duration of this project, the student will work in collaboration with, and have significant placement periods at both REMEDI, Galway (Ireland) and Jellagen Ltd (Pembroke Dock, Wales). The studentship will be predominantly based and registered at Swansea University Medical School (RBGO Group).


The applicant must be a self-motivated individual with an interest in the Life Sciences, and hold an undergraduate (BSc) degree (minimum classification 2:1) in a Life Sciences associated discipline (e.g. biology, biochemistry, medical engineering or biophysics). They should ideally also have basic laboratory experience (e.g. cell culture techniques, biochemical assays), a willingness to learn and have a basic level of information technology skills.
Desirable Characteristics: Advanced cell culture experience; experience of hydrogel technology and excellent communication skills/working with people.
Due to funding restrictions, this studentship is open to UK/EU students only.


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The studentship covers the full cost of UK/EU tuition fees, plus a tax free stipend of £14,553 p.a.


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