Computational genomics of UV-induced DNA damage
Subject area description
We are interested in how mutations arise and distribute across genomes, in both protein coding and non-coding DNA and with particular focus on ultraviolet (UV) light and skin cancers. For these studies we make use of publicly available as well as in-house generated genomic datasets, including genome-wide mapping of UV-induced DNA damage by high-throughput sequencing (CPD-seq). We now seek a skilled computational scientist to help address new challenges that will be tackled using this approach and related methods, in human cancer and beyond.
The project will involve bioinformatics analysis of large-scale genomic data generated in our lab, including integration with relevant public datasets. Although the emphasis will be on applied genomic science, development of new bioinformatics methodology may also be required to meet project goals. The work will be carried out in collaboration with experimental scientists. Relevant recent publications from our group include: Elliott et al., Nature Rev. Cancer 2021; Van den Eynden et al., Nature Genetics 2019, Lindberg et al, PNAS 2019; Elliott et al., Plos Genetics 2018; Fredriksson et al., Plos Genetics 2017; Fredriksson et al., Nature Genetics 2014. See www.larssonlab.org for more information.
An achieved doctoral degree is compulsory for a position as postdoctor at the University of Gothenburg. The doctoral thesis shall be in a relevant area according to the specific position stated here. Since a position as postdoctor aims to give new holders of the doctorate the opportunity mainly to strengthen and develop their scholarly proficiency, we aim for those who have a doctoral degree not older than 3 years counting from last date of application.
Good programming skills and linux/unix experience is a requirement. Knowledge of Matlab or R is desired. Previous experience with analysis of next-generation sequencing data is recommended. While not required, experience from relevant biological fields is desirable, and the applicant is expected to have published several articles in peer-reviewed journals. Excellent communicative skills are required, including fluency in oral and written English.
The qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.
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The employment is full time and temporary, two years, with placement at the Institute of Biomedicine. First day of employment as agreed.
In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.
The application should contain:
A cover letter giving a brief description of previous research experience, and a motivation to why you are applying
A CV including a list of publications
Proof of completed PhD
Contact details of two references